Name: AF488 Anti-Mouse CD274/PD-L1 Antibody [10F.9G2] (0.5 mg/mL) for FCM
Price: 298.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
- Properties
  - Host
    
    rat
    
    Isotype
    
    IgG2b kappa
    
    Reactivity
    
    mouse
    
    Conjugate
    
    AF488
    
    Formulation
    
    Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
    
    Storage
    
    This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.
    
    Concentration
    
    0.5 mg/mL
    
    Antigen
    
    B7-H1, PD-L1, Programmed cell death ligand 1, B7 homolog 1, B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1, (Gene ID:60533)
    
    * For reference only.
- Applications
  - Application
    
    FCM

AF488 Anti-Mouse CD274/PD-L1 Antibody [10F.9G2] (0.5 mg/mL) for FCM

AF488 Anti-Mouse CD274/PD-L1 Antibody [10F.9G2] (0.5 mg/mL) for FCM

Background

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