AES cDNA

- Overview
  - Amino-terminal enhancer of split, also known AES, belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. This protein is expressed predominately in fetal brain, liver, lung, heart and kidney and in adult muscle. In addition, AES can repress NFkB-regulated gene expression and is thought to play an important role in initiating and maintaining cell differentiation events.
    
    PRODUCT INFORMATION
    Antigen Species: Human
    NCBI Accession No: NP_001121.2
    RNA Reference Number: NM_001130.5
    OMIM Number: 600188
    Chromosome Location: 19p13.3
    cDNA size: 594bp
    Vector description: This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
    
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- Properties
  - Protein Name
    
    AES-1, AES-2, ESP1, GRG, Grg-5, GRG5, TLE5
    
    Type
    
    cDNAs
    
    Formulation
    
    Lyophilized
    
    Storage
    
    Store the plasmid at -20°C.
    
    Sequence
    
    Nucleotide Sequence: ATGATGTTTC CACAAAGCAG GCATTCGGGC TCCTCGCACC TACCCCAGCA ACTCAAATTC ACCACCTCGG ACTCCTGCGA CCGCATCAAA GACGAATTTC AGCTACTGCA AGCTCAGTAC CACAGCCTCA AGCTCGAATG TGACAAGTTG GCCAGTGAGA AGTCAGAGAT GCAGCGTCAC TATGTGATGT ACTACGAGAT GTCCTACGGC TTGAACATCG AGATGCACAA ACAGGCTGAG ATCGTCAAAA GGCTGAACGG GATTTGTGCC CAGGTCCTGC CCTACCTCTC CCAAGAGCAC CAGCAGCAGG TCTTGGGAGC CATTGAGAGG GCCAAGCAGG TCACCGCTCC CGAGCTGAAC TCTATCATCC GACAGCAGCT CCAAGCCCAC CAGCTGTCCC AGCTGCAGGC CCTGGCCCTG CCCTTGACCC CACTACCCGT GGGGCTGCAG CCGCCTTCGC TGCCGGCGGT CAGCGCAGGC ACCGGCCTCC TCTCGCTGTC CGCGCTGGGT TCCCAGGCCC ACCTCTCCAA GGAAGACAAG AACGGGCACG ATGGTGACAC CCACCAGGAG GATGATGGCG AGAAGTCGGA TTAG
    Translation Sequence: MMFPQSRHSG SSHLPQQLKF TTSDSCDRIK DEFQLLQAQY HSLKLECDKL ASEKSEMQRH YVMYYEMSYG LNIEMHKQAE IVKRLNGICA QVLPYLSQEH QQQVLGAIER AKQVTAPELN SIIRQQLQAH QLSQLQALAL PLTPLPVGLQ PPSLPAVSAG TGLLSLSALG SQAHLSKEDK NGHDGDTHQE DDGEKSD.
    
    * For research use only. Not intended for human, diagnostics or veterinary use.
- Applications
  - Application Description
    
    (1) Centrifuge at 7000rpm for 1 minute. (2) Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid.

AES cDNA

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