Adalimumab Biosimilar - Research Grade, Low Endotoxin

Adalimumab Biosimilar - Research Grade, Low Endotoxin

Catalog Number:
A001437351ICH
Mfr. No.:
ICH4001
Price:
$560
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      • Overview
        • Antigen Distribution: Activated monocytes, neutrophils, macrophages, T cells, B cells, NK cells, LAK cells
          Specificity: Detects human TNF alpha. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Adalimumab.
          Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
          Isotype Control: Bulk Human IgG1 Isotype Control (IB1) [ICH2254]
          Endotoxin: ≤ 0.75 EU/mg as determined by the LAL method

          Please contact us at for specific academic pricing.

          Background

          Adalimumab biosimilar is a recombinant human IgG1 monoclonal antibody specific for human tumor necrosis factor (TNF),was created using phage display technology resulting in an antibody with human derived heavy and light chain variable regions and human IgG1:k constant regions. Adalimumab biosimilar is produced by recombinant DNA technology in a mammalian cell (Chinese Hamster Ovary) expression system and is purified by a process that includes specific viral inactivation and removal steps. It consists of 1330 amino acids and has a molecular weight of approximately 148 kilodaltons.

      • Properties
        • Host
          humanized
          Isotype
          IgG1 kappa
          Reactivity
          human
          Purification
          >95% by SDS-PAGE and HPLC
          Formulation
          Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
          Storage
          Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
          Molecular Weight
          1.0 - 5.0 mg/ml

          * Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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