ACTL7B Polyclonal Antibody

ACTL7B Polyclonal Antibody

Catalog Number:
A001512563RED
Mfr. No.:
RD87635A
Price:
$416
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      • Overview
        • Calculated MW: 21-34kDa/83-85kDa
          Observed MW: 86kDa

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          Background

          The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein of human ACTL7B
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.01% thiomersal,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1mg/mL
          Antigen
          ACTL7B, Tact1 (Gene ID:10880; UniProt:Q9Y614)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:1000-1:2000

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