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4-Methylumbelliferone (Hymecromone; 4-MU)

4-Methylumbelliferone (Hymecromone; 4-MU)

Catalog Number:
L002438877INV
Mfr. No.:
V1976
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      • Overview

        • 4-Methylumbelliferone (Hymecromone; 4-MU) is a potent and selective inhibitor of hyaluronic acid (HA) biosynthesis with an IC50 of 0.4 mM. The activation of HAS2 and the over-production of HA are existed in many metastatic tumor cell lines. Increased synthesis of HA is often associated with increased metastatic potential and invasivity in tumor cells. 4-Methylumbelliferone (MU), an inhibitor of HA synthesis, has been studied as a potential anti-tumor drug on account of inhibiting the growth of primary tumors and distant metastasis of tumor cells.

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      • Properties
        • Categories
          Disease Research Fields
          CAS Number
          90-33-5
          Molecular Formula
          C10H8O3
          Molecular Weight
          176.17
          Purity
          ≥98%
          Storage
          Powder: store in -20°C freezer for up to three years, store in 4°C freezer for up to two years
          In solvent: store in -80°C freezer for up to six months, store in -20°C freezer for up to two months
          Shipping
          Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
          SMILES
          O=C1C=C(C)C2=CC=C(O)C=C2O1

          * For research use only

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