Name: Recombinant Human FGF2 (Fibroblast Growth Factor 2)
Price: Inquiry

- Overview
  - FGF-basic is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described. The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. Fibroblast Growth Factor-2 Human Recombinant (FGF-2) produced in E. Coli is a single, non-glycosylated, polypeptide chain containing 155 amino acids and having a molecular mass of 17250 Dalton. Human FGF2 is purified by proprietary chromatographic techniques. Cat# 32-9091
    
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- Properties
  - Protein Name
    
    FGF-2; bFGF; FGFB; HBGF-2
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    >98.0% as determined by Gel filtration at non denaturing conditions using 25 nM Tris-HCl + 150 nM NaCl, pH 8 and Analysis by reducing and non-reducing SDS-PAGE gel
    
    Formulation
    
    The protein was lyophilized from a concentrated (0.5 mg/ml) solution of PBS.
    
    Storage
    
    Lyophilized hFGF-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution and filter sterilization hFGF-2 should be aliquoted and frozen. For long term storage and more diluted solutions it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.
- Applications
  - Application Description
    
    Less than 0.05 ng/µg (0.5 EU/µg) of hFGF-2.

Recombinant Human FGF2 (Fibroblast Growth Factor 2)

Recombinant Human FGF2 (Fibroblast Growth Factor 2)

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