PTPN14 Mouse Monoclonal Antibody

PTPN14 Mouse Monoclonal Antibody

Catalog Number:
A001452237ZEN
Mfr. No.:
Zen-222965
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      • Overview
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          Background

          The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia.

      • Properties
        • Host
          mouse
          Isotype
          Mouse IgG1
          Reactivity
          human
          Immunogen
          Purified recombinant fragment of human PTPN14 expressed in E. Coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Purified antibody in PBS with 0.05% sodium azide
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Antigen
          (Gene ID:5784; UniProt:Q15678)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          IHC-P; ICC/IF; FC; ELISA
        • Application Dilutions
          IHC 1/100-1/200
          IF 1/50-1/200
          FC 1/50-1/100
          ELISA 1/10000

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