Anti-FGB Monoclonal Antibody (8E5)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC047	Anti-FGB Antibody (8E5)	Mouse IgG1, Kappa	None	$460	In stock	Add
ASPC047-P	Anti-FGB Antibody (8E5), PE	Mouse IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC047-A	Anti-FGB Antibody (8E5), APC	Mouse IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC047-H	Anti-FGB Antibody (8E5), HRP	Mouse IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC047-B	Anti-FGB Antibody (8E5), Biotin	Mouse IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC047

Anti-FGB Antibody (8E5)

Mouse IgG1, Kappa

None

$460

In stock

Add

ASPC047-P

Anti-FGB Antibody (8E5), PE

Mouse IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC047-A

Anti-FGB Antibody (8E5), APC

Mouse IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC047-H

Anti-FGB Antibody (8E5), HRP

Mouse IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC047-B

Anti-FGB Antibody (8E5), Biotin

Mouse IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-FGB Monoclonal Antibody (8E5)
- Product Description:
  
  The 8E5 antibody is a fibrin-specific monoclonal antibody that recognizes the β-chain of fibrin, accessible only after the conversion of fibrinogen to fibrin by thrombin.
  
  Applications:
  
  Functional Assay, Enzyme-Linked Immunosorbent Assay
  
  Source:
  
  Mouse
  
  Target:
  
  FGB
  
  Target Species:
  
  Human
  
  Specificity:
  
  The beta-chain of human fibrin
  
  Immunogen:
  
  A synthetic β-fibrin peptide
  
  Epitope:
  
  GHRPLDKC
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  8E5
  
  Isotype:
  
  Mouse IgG1, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-FGB Monoclonal Antibody (8E5) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

FGB

Protein Name

Fibrinogen beta chain

Introduction

The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

Alternative Names

Fibrinogen Beta Chain; Fibrinogen, B Beta Polypeptide; Epididymis Secretory Sperm Binding Protein Li 78p; Beta-Fibrinogen; HEL-S-78p

Gene ID

2244

UniProt

P02675

Related Disease

Congenital afibrinogenemia (CAFBN)

Subcellular Location

Endoplasmic reticulum

Tissue Specificity

Detected in blood plasma (at protein level).

Cell Type

Embryonic Stem Cells, Hematopoietic stem and progenitors, Leukemia, Mast cells, Mesenchymal Stem Cells

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