Anti-EGFR Monoclonal Antibody (7A7)

Anti-EGFR Monoclonal Antibody (7A7)

Cat No: ASPC006

Summary
Host Species:
Mouse
Species Reactivity:
Human, Mouse
Applications:
Functional Assay, Flow Cytometry, Immunofluorescence, Immunohistochemistry
Clone ID:
7A7
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Availability Quantity
ASPC006 Anti-EGFR Antibody (7A7) Mouse IgG1, Kappa None $460 In stock
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ASPC006-P Anti-EGFR Antibody (7A7), PE Mouse IgG1, Kappa PE $1,180 2-3 weeks
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ASPC006-A Anti-EGFR Antibody (7A7), APC Mouse IgG1, Kappa APC $980 2-3 weeks
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ASPC006-H Anti-EGFR Antibody (7A7), HRP Mouse IgG1, Kappa HRP $600 2-3 weeks
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ASPC006-B Anti-EGFR Antibody (7A7), Biotin Mouse IgG1, Kappa Biotin $680 2-3 weeks
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ASPC006-4 Anti-EGFR Antibody (7A7), Fc Silenced Mouse IgG1, Kappa Fc Silenced None $980 4-6 weeks
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-EGFR Monoclonal Antibody (7A7)
    • Product Description:
      The 7A7 antibody is a monoclonal antibody that specifically recognizes the extracellular domain of the human Epidermal Growth Factor Receptor (EGFR). EGFR is a transmembrane receptor tyrosine kinase that plays a critical role in regulating cell growth, survival, proliferation, and differentiation.
      Applications:
      Functional Assay, Flow Cytometry, Immunofluorescence, Immunohistochemistry
      Source:
      Mouse
      Target:
      EGFR
      Target Species:
      Mouse
      Specificity:
      The extracellular domain of human EGFR
      Immunogen:
      Recombinant Mouse EGFR protein
      Clonality:
      Monoclonal
      Clone ID:
      7A7
      Isotype:
      Mouse IgG1, Kappa
      Purification:
      The antibody was purified by Protein A.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Concentration:
      1 mg/mL
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for customized product form or formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-EGFR Monoclonal Antibody (7A7) Applications
    • Note:
      Optimal dilutions/concentrations should be determined by the end user.
Gene Symbol
EGFR
Protein Name
Epidermal growth factor receptor
Molecular Family
CD Molecules, Growth Factors
Introduction
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Alternative Names
Epidermal Growth Factor Receptor; Receptor Tyrosine-Protein Kinase ErbB-1; Erb-B2 Receptor Tyrosine Kinase 1; Proto-Oncogene C-ErbB-1; EC 2.7.10.1; ERBB1; ERBB; HER1; Epidermal Growth Factor Receptor (Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog); Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog (Avian)
Gene ID
UniProt
Related Disease
Lung cancer (LNCR)
Subcellular Location
Nucleoplasm,Nucleoli,Plasma membrane,Cell Junctions
Tissue Specificity
Ubiquitously expressed. Isoform 2 is also expressed in ovarian cancers.
Cell Type
B cells, T cells, Thymocytes, Tregs
Function
EGFR signaling, cell signaling
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