Anti-Human TPBG Monoclonal Antibody

Subcat	Description	Isotype	Conjugate	Price
ASPC1397	Anti-Human TPBG Antibody	Mouse IgG1, Kappa	None	$460	Add
ASPC1397-A	Anti-Human TPBG Antibody, APC	Mouse IgG1, Kappa	APC	$980	Add
ASPC1397-B	Anti-Human TPBG Antibody, Biotin	Mouse IgG1, Kappa	Biotin	$680	Add
ASPC1397-H	Anti-Human TPBG Antibody, HRP	Mouse IgG1, Kappa	HRP	$600	Add
ASPC1397-P	Anti-Human TPBG Antibody, PE	Mouse IgG1, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC1397

Anti-Human TPBG Antibody

Mouse IgG1, Kappa

None

$460

Add

ASPC1397-A

Anti-Human TPBG Antibody, APC

Mouse IgG1, Kappa

APC

$980

Add

ASPC1397-B

Anti-Human TPBG Antibody, Biotin

Mouse IgG1, Kappa

Biotin

$680

Add

ASPC1397-H

Anti-Human TPBG Antibody, HRP

Mouse IgG1, Kappa

HRP

$600

Add

ASPC1397-P

Anti-Human TPBG Antibody, PE

Mouse IgG1, Kappa

$1,180

Add

Anti-Human TPBG Monoclonal Antibody
- Product Description:
  
  The Anti-TPBG antibody is a mouse monoclonal antibody recommended for use in flow cytometry, enzyme-linked immunosorbent assay, functional assay and other applications. This antibody specifically targets TPBG and demonstrates reactivity with human.
  
  Applications:
  
  Flow Cytometry, Enzyme-Linked Immunosorbent Assay, Functional Assay
  
  Source:
  
  Mouse
  
  Target:
  
  TPBG
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with Human TPBG.
  
  Immunogen:
  
  Human TPBG.
  
  Clonality:
  
  Monoclonal
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-Human TPBG Monoclonal Antibody Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

TPBG

Protein Name

Trophoblast glycoprotein

Introduction

This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein.

Alternative Names

5T4; 5T4AG; M6P1; WAIF1

Gene ID

7162

UniProt

Q13641

Subcellular Location

Cell membrane

Tissue Specificity

Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.

Cell Line Specificity

Low cancer specificity

Function

May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.

Customer Reviews

There are no reviews for Product Name.

Submit a review and receive an Amazon gift card.

Publications

There are no publications for Product Name.

If you couldn't find the specific publication, you can:
Submit a Citation Get a Publication Reward