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Overview
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Thalidomide is an antimalignancy cancer research compound that has shown antiangiogenic and immunomodulatory activities.
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Background
The exact mechanism of thalidomide is unknown, however it has been shown to inhibit TNF-α, IL-6, IL-10 and IL-12 production while enhancing the production of IL-2, IL-4 and IL-5. It also effects natural killer cell toxicity and stimulates T lymphocytes.
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Overview