Imipramine hydrochloride

- Overview
  - Imipramine hydrochloride is a hydrochloride salt form of imipramine, a surface active tricyclic drug, a potent inhibitor of serotonin and norepinephrine reuptake. It has a greater affinity for the serotonin and it has more anticholinergic side effects which can be helpful in treating enuresis. Imipramine blocks D-2 receptors, H1 receptors, alpha 1 and alpha 2 adrenergic receptors and muscarinic receptors. It is used for therapy of depression (major and bipolar) and nocturnal enuresis in children. Also it is indicated for dysthymia, attention-deficit disorders, agoraphobia and it is effective in treating anxiety and panic disorders.
    
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- Properties
  - Categories
    
    Ligands of Transporters
    
    Alternative Name
    
    10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine hydrochloride; Chrytemin; Imiprin
    
    CAS Number
    
    113-52-0
    
    Molecular Formula
    
    C19H25ClN2
    
    Molecular Weight
    
    316.87 g/mol
    
    MDL Number
    
    MFCD00012669
    
    Note
    
    There is no hazardous surcharge associated with this product.
    There is no special packaging charge associated with this product.
    
    * For research use only. Not for human or veterinary use
- Reference
  - Ruben Vardanyan, Victor Hruby (2016). Synthesisof Best-Seller Drugs, Antidepressants 111-143.
    Fayez, R., Gupta, V. et al, (2020). Imipramine. StatPearls. Ncbi.nlm.nih.gov.