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Overview
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Gastrodin (Gastrodine), a brain-penetrant anti-inflammatory polyphenol extracted from Chinese natural herbal Gastrodia elata Blume, benefits neurodegenerative diseases. Gastrodin is the most important and effective ingredient extracted from Chinese natural herbal Gastrodia elata. Gastrodin (30, 40, and 60 mM) significantly attenuates levels of neurotoxic proinflammatory mediators and proinflammatory cytokines by inhibition of the NF-kappaB signaling pathway and phosphorylation of MAPKs in LPS-stimulated microglial cells.
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Overview