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Overview
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Introduction
Cdc42 (mol. wt. 21 kDa) belongs to the Rho-family of small G-proteins. The Rho family consists of at least 22 members, the most extensively characterized of which are the Rac1, RhoA and Cdc42 proteins. In common with all other small G-proteins, Rho family proteins act as molecular switches that transmit cellular signals through an array of effector proteins. The family mediates a diverse number of cellular responses including cytoskeletal reorganization, regulation of transcription, apoptosis and neuronal morphology.
Proteins within the Rho-family share 40-95% amino acid identity within their GTPase domains.
Advantages
> ACD04 has superior lot-to-lot consistency: all Cytoskeleton Inc. antibodies are QC'd for highly reproducible signal and detection.
> ACD04 is priced favorably compared to other Cdc42 antibodies.
Material
The anti-Cdc42 antibody is a mouse monoclonal antibody. The antibody was raised against a peptide sequence of human Cdc42 (amino acids 150-182), it specifically recognizes Cdc42 in a wide range of species, including mammalian, reptile and avian and amphibian sources. Quality Control analysis has shown that the antibody does not recognize Rac1. ACD04 is supplied as a lyophilized white powder. Each Lot of antibody is quality controlled to provide a high batch to batch consistency.Please contact us at for specific academic pricing.
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- Properties
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Overview