AAV-Syn-SaCas9 (AAV Serotype 9) (Pre-made)

AAV9-Syn-SaCas9 is a pre-packaged rAAV in serotype 9 (capsid from AAV serotype 9 and 2xITR from AAV serotype 2) which over-expresses SaCas9 (Cas9 from Staphylococcus aureus) under human Synapsin promoter. T he size of the commonly used Cas9 from Streptococcus pyogenes (SpCas9) limits its utility for basic research and therapeutic applications that use the highly versatile AAV delivery vehicle. SaCas9 which is 1.0 kilobase shorter than SpCas9 can edit the genome with efficiencies and specificity similar to those of SpCas9 and be easily packaged into AAV vehicle. Ready to use format.

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