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Overview
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AAV (BI30) -CAG-GFP is a pre-packaged rAAV in serotype BI30 ( a capsid with tropism for CNS endothelial cells) which over-expresses EGFP under the CAG (also known as CBA) promoter. The CAG promoter is a combination of the cytomegalovirus (CMV) early enhancer element and chicken beta-actin promoter for high levels of gene expression in mammalian expression vectors. Compared with rAAV serotype 9, rAAV in serotype BI30 is able to penetrate brain-blood barrier (BBB) and infect CNS via tail vein I.V. with 50 times better transduction efficiency. Ready to use format.
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