5-Ethynyl-2'-deoxyuridine (5-EdU)

- Overview
  - Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Nucleoside analog of thymidine for fast and sensitive detection of DNA synthesis
    
    Alternative Name
    
    5-ethynyl-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
    
    CAS Number
    
    61135-33-9
    
    Molecular Formula
    
    C11H12N2O5
    
    Molecular Weight
    
    252.22
    
    Appearance
    
    Solution
    
    Purity
    
    98.02%
    
    Solubility
    
    ≥25.2 mg/mL in DMSO; insoluble in EtOH; ≥3.16 mg/mL in H2O with gentle warming and ultrasonic
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    O=C1C(C#C)=CN([[email protected]@H]2O[[email protected]](CO)[[email protected]@H](O)C2)C(N1)=O
    
    * For Research Use Only
- Reference
  - 1. Lulin Tan, Zhaojun Chen, et al. "MicroRNA Profiling Reveals an Abundant sscmiRNA-148a-3p that Promotes Proliferation and Differentiation during Intramuscular Adipogenesis in Chinese Guizhou Congjiang Pigs Breeds by targeting PPARGC1A." Research Square. rs-818015/v1.
    2. Nan Jiang, Hong Li, et al. "Network Pharmacology and Pharmacological Evaluation Reveals the Mechanism of the Sanguisorba Officinalis in Suppressing Hepatocellular Carcinoma." Front Pharmacol. 2021 Mar 4;12:618522. PMID:33746755