In the fields of drug delivery, advanced materials, treatment, and diagnosis, nanoparticles play a vital role due to their unique physical, chemical and biological properties. In order to efficiently and stably prepare nanoparticles with controllable particle size, uniform structure and precise functionalization, advanced nanoparticle processing systems have emerged to achieve precise synthesis, surface modification, dispersion stability, graded purification and final formulation of nanoparticles. Modern nanoparticle processing systems are constantly evolving and moving towards modularization, continuity, real-time monitoring and scalability to meet the different needs of each stage from early research and development to commercial production.
Nanoparticle processing systems cover the key steps of the entire process of nanoparticle preparation and post-processing, including mixing and nucleation, dilution and buffer replacement, concentration and purification, and surface functionalization modification. The systems usually rely on high-speed turbulent mixing or microfluidic mixing technology to achieve rapid nucleation and uniform particle growth of materials at the nanoscale.
According to different stages and scales of application, nanoparticle processing platforms can be classified into four categories: R&D platforms designed for small-volume process development and multi-parameter optimization; pilot-scale platforms that support process scale-up and validation; commercial production platforms that comply with GMP standards and are suitable for large-scale manufacturing; and downstream processing systems specialized in dilution, buffer exchange, concentration, and purification of nanoparticles.
Amerigo Scientific offers a variety of nanoparticle processing systems, including flexible and efficient small-scale equipment for research purposes, as well as GMP production systems for preparing for the expansion of production scale, to meet the requirements of achieving efficient, stable, and compliant nanoparticle production at different stages.
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