Single-use Systems

The use of single-use systems (also referred to as disposable technologies) has transformed the biopharmaceutical and biotechnology industries, providing flexible and efficient alternatives to traditional stainless-steel equipment. These systems are designed for single-use in specific processes and are composed of multiple components. They are mainly made of plastics such as polyethylene, polypropylene, and polycarbonate.

The single-use systems are almost involved in every step of the processing and manufacturing workflow. The main types of single-use systems include disposable vessels used for cell culture and fermentation, mixers for fluid preparation, filters for clarification and purification, as well as various assemblies such as bags, tubing, and connectors. They can be arranged and combined to form a complete and closed-system flow path. The modular nature of these components enables the creation of customized production solutions that are highly adaptable to specific needs of a particular process. Even complex operations like chromatography and tangential flow filtration can use single-use elements.

The significant feature of single-use systems is that they greatly reduce the risk of cross-contamination between different product batches. There is no need to clean and disinfect the equipment between uses, and the purity of subsequent batches is hardly affected by residual substances. Therefore, single-use systems significantly reduce the time and resource investment for cleaning verification, allowing for short batch cycles and enhancing production flexibility.

Amerigo Scientific offers high-quality and scalable single-use systems. The materials comply with the regulations of the international mainstream pharmacopoeia, and do not contain any ingredients derived from animals. The materials also process high physical and chemical stability as well as safety. Our products have undergone rigorous quality testing and can be applied in the biopharmaceutical or bioprocessing production process.