Products List

Filgiant® Sterilizing-grade Hydrophobic Filters

Sterilizing-grade hydrophobic filters are the core components used in industrial fields such as pharmaceuticals, biotechnology, food and beverage, and electronics to ensure the sterile state of gases and specific liquids. The most used material for hydrophobic sterilizing-grade filtration membranes is polytetrafluoroethylene (PTFE), which has extremely low surface energy and exhibits outstanding hydrophobic properties. Additionally, PTFE has strong chemical inertness and can withstand strong acids, strong bases, various organic solvents, and corrosive chemicals. This enables PTFE to be used for filtering corrosive non-aqueous liquids. The strong hydrophobic property makes filters an ideal choice for gas filtration. In humid air or steam environments, the filter membrane would not be wetted by condensation water and clogged, thus ensuring the stable flow of gases.

Filgiant® PTFE Sterilizing-grade Hydrophobic Filters

Amerigo Scientific offers Filgiant® sterilizing-grade hydrophobic filters, which are composed of single-layer or double-layer polytetrafluoroethylene (PTFE) membranes and polypropylene components. These filters possess excellent chemical compatibility and characteristics such as high flow rate, high flux, and no fiber shedding. Various filter sizes and connectors are available to meet extensive usage requirements.

Product	Nominal Size
Filgiant® Sterilizing-grade Hydrophobic Capsule Filter, 1 inch Size	1 inch
Filgiant® Sterilizing-grade Hydrophobic Capsule Filter, 2.5-20 inch Size	2.5 inch; 5 inch; 10 inch; 20 inch
Filgiant® Sterilizing-grade Hydrophobic Cartridge Filter	2.5 inch; 5 inch; 10 inch; 20 inch; 30 inch
Filgiant® Sterilizing-grade Hydrophobic Disk Filter	dia. 50mm

Product Features

The filter membrane made of PTFE, withstanding multiple sterilization cycles;
Retaining particles of size down to 0.01μm though physical retention and charge adsorption;
High-temperature and high-pressure tolerance;
Good chemical compatibility, pH 1-14 tolerance;
Suitable for the scale ranging from R&D to manufacture

Filter Applications

Vent filters for storage tanks, fermentation tanks, and WFI tanks;
Gas sterile filtration of compressed air/clean pipelines;
Sterile filtration of input/output gases in bioreactors;
Sterile filtration of non-aqueous liquids

Product Parameters

Filter type		Disk Filter	Capsule Filter	Cartridge Filter
		Single layer/Double layer	Single layer/Double layer	Single layer/Double layer
Nominal size		Φ50mm	1/2.5/5/10/20 inch	2.5/5/10/20/30 inch
Membrane pore size		0.22μm/0.22+0.22μm
Effective filtration area		13.8cm²	0.04/0.16/0.33/0.65/1.3m²	0.16/0.33/0.65/1.3/1.95m²
Filter components and structure	Filter membrane	Hydrophobic Polytetrafluoroethylene (PTFE)
	Support layer	Polypropylene (PP)
	Housing/structural components	Polypropylene (PP)
	Vent O-ring	Silicone	Silicone	--
	O-ring	--	--	Silicone/EPDM/FKM
Maximum operating differential pressure		Forward:5.5bar (80psi) at 25°C; 1.7 bar (25psi) at 80°C	Forward:5.5bar (80psi) at 25°C; 1.7 bar (25psi) at 80°C	Forward:5.5bar (80psi) at 25°C; 1.7 bar (25psi) at 80°C
		Reverse:2.1bar (30psi) at 25°C	Reverse:2.1bar (30psi) at 25°C	Reverse:2.1bar (30psi) at 25°C
Maximum inlet pressure		--	0.65Mpa	--
Bubble point		≥1100mbar (100%, IPA bubble point at 25°C)
Water intrusion (at 2500mbar)		2.5 inch:≤0.2ml/min; 5 inch:≤0.4ml/min; 10 inch:≤0.8ml/min; 20 inch:≤1.6ml/min
Sterilization resistance		Offline: 126 °C /60 minutes, 3 times	Offline :126°C/30 minutes, 30 times (SIP not allowed)	Offline :126°C/60 minutes, 50 times SIP: Forward :142°C/30 minutes, 200 times Reverse :126°C/60 minutes, 25 times (not exceeding the maximum operating pressure difference of cartridge)
Cleanliness		Complying with 21CFR21 0.3(b)(6) of "None fiber release"
Bacterial endotoxin		≤ 0.25 EU/ml
Biosafety test		All materials of the filter element meet USP <88> , Class VI -70°C biosafety evaluation of plastic materials
Bacteria retention		The bacterial retention rate of products was tested according to the test method of ASTMF838 and with the defective Pseudomonas (ATCC19146), and the minimum retention rate was 10⁷cfu/cm².
Aerosol test		The retention rate for Brevundimonas diminuta (ATCC 19146) aerosol was tested referring to the requirements of PDA TR40, and the minimum retention rate was 10⁷cfu/cm².

Pressure Drop and Gas Flowrate

Figure 1. Filgiant® Hydrophobic Gas Filter (0.22μm) - Pressure Drop and Gas Flowrate

Related Products

SaiPress® Sterilizing-grade Hydrophilic Filters

Amerigo Scientific offers SaiPress® PES hydrophilic filters with high flux and high capacity and SaiPress® PVDF hydrophilic filters with high porosity and low protein adsorption. A variety of specifications are available to meet different requirements of sterilization filtration for liquids.

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