APSNDB Sterilizing-Grade Liquid Filter

Cat. No.	Specification	Unit	Price	Quantity
FCM1504292-01	Membrane: Hydrophilic polyethersulfone (PES)	each	Inquiry

Product Description

Product Description

Very low adsorption using a single-layer hydrophilic asymmetric polyethersulfone membrane

Quality:
· 100% Integrity testing in manufacturing
· Each filter is fully traceable with unique serial number
· Manufactured in a facility which adheres to ISO 9001:2015 Practices

Features

· Hydrophilic polyethersulfone membranes offer very low adsorption and broad chemical compatibility
· Asymmetric membranes for higher loading capacity and lower costs
· Sterilization for simple solvents, effective bacterial reduction for some complex fluid applications

Specifications

Materials of Construction

Membrane	Hydrophilic polyethersulfone (PES)
Support	Polypropylene (PP)
Core/Cage/End Caps	Polypropylene (PP)
End Cap Inserts	Polybutylene terephthalate (PBT)
Seal Material	Silicone / EPDM / Viton FEP/ PFA encapsulated O-rings

Operating Conditions

Max. Operating Temperature	80°C
Max.Operating Pressure	0.69 MPa@25°C 0.40 MPa@60°C 0.24 MPa@80°C
Max. Differential Pressure (Forward)	0.69 MPa@25°C 0.40 MPa@60°C 0.24 MPa@80°C
Max. Differential Pressure (Reverse)	0.30 MPa@25°C 0.10 MPa@80°C

Filtration Area

Outer Diameter	Membrane Pore Size	Area/10'
69mm	0.22μm	0.55m²

Integrity Standard @10inch, 20°C

Membrane Pore Size	Bubble Point
0.22μm	≥ 0.32 MPa (water), Air test

Bacterial Retention

Model	Content
APSNDB 0.22μm	Bacterial quantitative retention of 10⁷ cfu/cm² Brevundimonas diminuta (ATCC 19146) accordingto ASTM F838 methodology.

Sterilization

In-line steam sterilization

Up to 30 cycles (135°C for 30 min and differential pressure < 30 kPa per cycle)

Regulatory Compliance

Autoclaved filter effluent meets the USP<788> requirement of particulate matter in large volume injection.
Component materials meet the criteria for a' Non-fiber-releasing filter' as defined in 21 CFR 210.3(b)(6).
Aqueous extraction from a cartridge contains less than 0.25EU/ml as determined by Limulus Amebocyte Lysate (LAL), meeting requirements of USP<85>.
Meet the requirement of USP <87> In Vitro Cytotoxicity Test.
Component materials meet the requirements of the current USP<88> for plastic class VI-121°C.
All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182.
Based on the current information from our suppliers, all component materials used in the manufacture of this product are animal-free.

Ordering Information:

Outer Diameter	Type	Membrane Pore Size	End Cap	Nominal Length	Seal Material	Industry
69mm	APSNDB	0022 0.22µm	DOE Double Open End	05 5 inch	S Silicone	P
			HTF 222/Fin	10 10 inch	E EPDM
			HSF 226/Fin	20 20 inch	V Viton
			HTCG 222/Flat	30 30 inch	P FEP/PFA encapsulated O-rings
			HSCG 226/Flat	40 40 inch

* Example: APSNDB0022DOE05SP (DPSHSL, 0.22+0.1µm, Double Open End, 5 inch, Silicone, Pharmaceutical)

Applications

Application Description

Buffer sterile filtration