Analytical Supercritical Fluid Chromatography

The analytical supercritical fluid chromatograph uses supercritical fluid (such as CO2) with good dissolution and mass transfer characteristics as the mobile phase, and optimizes the analysis and preparation conditions by adjusting the flow rate and composition of the mobile phase, as well as the system temperature and pressure.

· Usually, a elution flow rate of 3-5 times HPLC is used, making analysis faster and preparation more time-saving;
· Using CO2 and a small amount of modifier as the mobile phase for analysis and preparation is more green and environmentally friendly;
· Suitable for some hydrophilic macromolecules and able to maintain biological activity;
· The retention behavior differs significantly from GC and HPLC, and complements traditional separation m2ethods.