Rainbow R6 for QC and R&D - In Situ Fiber Optic UV-Vis Spectrometer

The in situ fiber optic UV-Vis spectrometer enables real-time concentration monitoring for dissolution, absorption, and solubility studies.

· 5 different advanced mathematical approaches to deal with turbidity or other disturbances in the spectrum, making in situ monitoring work
· Its Green. No filters, HPLC vials, columns or eluents. Everything is done in your experiment vessel
· Direct measurements in complex or biorelevant media, even with media conversion is possible in small, biorelevant or USP volume
· No separation is needed. Multiple mathematical ways to measure 2-3(-4) absorbing components in the vessel, all in real time

Dissolution Testing; Absorption; Solubility Studies
Oral Formulation Delivery; Injectable Formulation Delivery

Coupled with dissolution bath
· Small volume dissolution testing
· Solubility measurement
· Dissolution rate and IDR measurements
· Supersaturation-precipitation studies
· Salt and polymorph selection
Coupled with dissolution-permeation (flux) system:
· Absorption prediction
· Prediction of the rate limiting step of absorption
· Bioequivalence prediction
· Formulation excipient effect screening
· Formulation strategy selection
Coupled with Subcutaneous Injection site simulator (Scissor):
· Biosimilar characterization
· Injectable formulation rank ordering
· De-risking formulation issues upon injection