MicroDISS In Situ Fiber Optic UV Monitoring System

Insitu fiber optic UV monitoring system for small volumes of 2- 20 ml
· Designed to monitor concentration in real-time
· Powered by AuPRO™
· Most comprehensive dissolution data analysis software in the industry
· Evaluate solubility, intrinsic disc dissolution rate, dissolution profiles, supersaturation, precipitation patterns
· User-friendly graphic display
· Simultaneous real-time data collection and analysis

· Versatile
Smart software and flexible architecture allow for multiple experimental conditions on a single platform.
· ‍Robust
The MicroDISS Profiler™ employs dip-style probes engineered in stainless steel.
· ‍Fast and Accurate
Up to 8 individual Photo Diode Array Spectrophotometers allow data collection of UV/VIS spectra (200 – 720 nm) at 1nm resolution as often as every two seconds from all vessels simultaneously. Allows to work with variety of volumes and stirring speeds within a single experimental set up.
· ‍Cost-effective
Ideal for small volume dissolution (2-20 mL), with interchangeable pathlength tips to bring the cost-efficiencies of combined speed and flexibility.

Oral Formulation Delivery; Physicochemical Characterization

Small volume dissolution – tablets, capsules, powders and films
Intrinsic dissolution of miniaturized compressed pellets
Biorelevant dissolution
Excipients and salts screening
Dynamic media composition change
Polymorphic changes and precipitation patterns
Intrinsic and Kinetic Solubility in – Aqueous and Non-Aqueous Media
Solution stability of drug candidates
Nanoparticle solubility and dissolution
Supersaturation studies
Micro- and nanonization effects on dissolution