Proteomix POR IEX - Ion Exchange Chromatography

Cat. No.	Description	Specification	Unit	Price
CC02501882-01	Pre-packed Column	Proteomix POR15-Q (15 µm, 1000 Å),	Each	Inquiry
CC02501882-02	Pre-packed Column	Proteomix POR15-S (15 µm, 1000 Å),	Each	Inquiry
CC02501882-03	Pre-packed Column	Proteomix POR30-Q (30 µm, 1000 Å),	Each	Inquiry
CC02501882-04	Pre-packed Column	Proteomix POR30-S (30 µm, 1000 Å),	Each	Inquiry
CC02501882-05		Proteomix POR15-Q (15 µm, 1000 Å), 7.5 x 100mm, 4.2mL	Each	Inquiry
CC02501882-06		Proteomix POR15-S (15 µm, 1000 Å), 7.5 x 100mm, 4.2mL	Each	Inquiry
CC02501882-07		Proteomix POR30-Q (30 µm, 1000 Å), 7.5 x 100mm, 4.2mL	Each	Inquiry
CC02501882-08		Proteomix POR30-S (30 µm, 1000 Å), 7.5 x 100mm, 4.2mL	Each	Inquiry

Product Description

Product Description

Proteomix POR ion exchange resin is specifically designed for the separation and purification of biological samples. Proteomix POR-S/Q is based on the uniform PS/DVB beads with particle size of 15/30 μm. It has good physical and chemical stability with better pressure resistance.

The Proteomix POR-S/Q resin surface is modified with a unique coating technology, which is highly hydrophilic and minimizes non-specific binding with biological samples. Through proprietary surface modification technology, different spacer arms and ion exchange functional groups are bonded on the surface of hydrophilic matrix to obtain strong cation exchange (S), strong anion exchange (Q) and other chromatographic media, and ensure the high density and uniformity of the surface ion exchange layer. Proteomix POR-S/Q ion exchange resin can be widely used for the separation and purification of biological samples such as vaccines, insulin, protein, nucleic acid, etc.

Features

• High binding capacity and excellent biocompatibility
• Rigid beads can be operated under high pressure and fast flow rate
• High resolution, efficiency, and recovery
• High batch-to-batch reproducibility
• Easy to scale up
• Highly hydrophilic surface, negligible non-specific binding
• Small volume change under standard packing condition

Specifications

Resin Type	Proteomix POR IEX	Proteomix POR15-Q	Proteomix POR30-S	Proteomix POR30-Q
Matrix	Hydrophilic modified polystyrene/divinylbenzene (PS/DVB)		Hydrophilic modified polystyrene/divinylbenzene (PS/DVB)
Functional Group	-SO3H	-N+(CH3)3	-SO3H	-N+(CH3)3
Particle Size	15 μm	15 μm	30 μm	30 μm
DBC (per mL resin)	≥40 mg Lysozyme	≥40 mg BSA	≥40 mg Lysozyme	≥40 mg BSA
Maximum Linear Flow Rate	1800 cm/h		2000 cm/h
Recommended Linear Flow Rate for Optimal Result	150-900 cm/h		300-1000 cm/h
Operation Temperature	4-40 °C		4-40 °C
pH Range	2-13	2-12	2-13	2-12
Maximum Pressure	≤15 MPa (150 bar)
Compatible Mobile Phases	Compatible with aqueous solution, a mixture of water and acetonitrile, ethanol, etc. Typical buffers: Tris, phosphate, and acetate
Storage	20% ethanol or 2% benzyl alcohol
Regeneration	1-2 M NaCl, or 0.5-1.0 M NaOH
CIP	0.5 M HCl or 0.5-1.0 M NaOH. Impurities with strong hydrophobic binding can be cleaned with 0.1-1% Tween

* Dynamic Binding Capacity Test Method: Proteomix POR15-S/30-S: linear flow rate at 360 cm/h; Sample solution is 50 mM phosphate buffer with 1 mg/mL lysozyme (pH=6.0). Proteomix POR15-Q/30-S: The linear flow rate at 180 cm/h; Sample solution is 50 mM Tris buffer with 2 mg/mL BSA (pH=8.5).