Flexible Tangential Flow Filtration Device

Our Flexible Tangential flow filtration devicesto suit your specific process needs. Flexible Tangential flow filtration devicesstandard systems are ready-to-use, engineered systems with integrated recipe management tools to expedite your approval processes and reduce your time to market.
The pilot system includes the flexibility of both semi and full automation, a UV detector, a pH monitor, an Integrity Analyzer, and an integrated tank. The system expedites the development and scale-up of filtration processes in accordance with FDA cGMP regulations and guidelines.

Microfiltration (MF) is useful in the early stages of downstream processing for the "recovery" or isolation of bio-product away from bioreactor waste-material and micro-particulates. MF helps to clarify the feed in the upstream harvest. Microfiltration can be used to separate microorganisms and suspended particles ranging from .1 to 10 μm in size.

Ultrafiltration (UF) can be introduced to the intermediate phase of the downstream process, preceding or following purification chromatography. Here, UF is an effective method for protein concentration and buffer exchange prior to the polishing chromatography phase. Ultrafiltration separates macro-molecules ranging from 0.001 to 0.1 μm in size.