Butyl Bestarose 4FF - Butyl HIC Chromatography Columns

Hydrophobic interaction chromatography (HIC) is a chromatographic method that uses the interaction between the hydrophobic groups carried by biological molecules and the hydrophobic ligands on the stationary phase to separate substances. Salt ions can destroy the hydration membrane on the surface of biomolecules and promote the binding between hydrophobic groups and ligands.
Butyl Bestarose 4FF is formed by coupling butyl chain on 4% agarose base matrix. The High physical and chemical stability of agarose base matrix provides it with good pressure flow velocity performance, making it an ideal choice for large-scale purification process, especially in the capture or intermediate purification stages where a high flow velocity separation process is required. The optimized ligand concentration is suitable for the separation and purification of biological molecules with strong hydrophobicity.