Automated Tangential Flow Filtration System

Automated TFF Systems for Scalable Processing offers scalable, Automated TFF systems to suit your specific process needs. Our Standard systems are ready-to-use, engineered systems with integrated recipe management tools to expedite your approval processes and reduce your time to market.
The pilot TFF system includes the flexibility of both semi and full automation, a UV detector, a pH monitor, an Integrity Analyzer, and an integrated tank. The system expedites the development and scale-up of filtration processes in accordance with FDA cGMP regulations and guidelines.

Process Automation
Puts Control in the Hands of your Process Engineers.
User-friendly recipe management tools include a suite of default recipes for pre-production, production, and post-production operations. Your process experts can make applications work without waiting for programmers to sift through cryptic proprietary software code.
The flexible software design enables users to build recipes and develop processes without PLC programming expertise. Our software is ideal for use in a variety of environments, including process:
• Development
• Optimization
• Production

Why Use Tangential Flow Filtration?
1. Easy to set up and use - Simply connect the TFF device to a pump and pressure gauge(s) with tubing and a few fittings, add your sample to the reservoir, and begin filtration.
2. ast and efficient - It is easier to set up and much faster than dialysis. Higher concentrations can be achieved in less time than when using centrifugal devices or stirred cells.
3. Perform two steps with one system - Concentrate and diafilter a sample on the same system, saving time and avoiding product loss.
4. Can be scaled up or scaled down -Materials of construction and cassette path length allow conditions established during pilot-scale trials to be applied to process scale applications. TFF devices that can process sample volumes as small as 10 mL or as large as thousands of liters are available.
5. Economical - TFF devices and cassettes can be cleaned and reused, or disposed of after single use. A simple integrity test can be performed to confirm that membrane and seals are intact.