Prodigy 2.0 Peptide Purification System

Optimized purification using greener solvents.
The Prodigy 2.0™ is a unique preparative HPLC system that provides significantly higher recoveries while also enabling the complete replacement of acetonitrile with ethanol. It features a newly-developed integrated heating system1 that heats both the column and mobile phase, providing high-efficiency elevated temperature operation while overcoming the backpressure challenges associated with the higher viscosity of ethanol.
Cat. No. Unit Price Quantity
LCR1555629-01 Each Inquiry

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Product Description
Product Description
· Integrated Heating System
Heating at a uniform temperature for the best performance.
Traditional elevated temperature preparative chromatography approaches often focus on column heating only. While this can reduce the system backpressure, it introduces significant band broadening due to a mismatch of temperature between the column wall and the cold incoming mobile phase.

· The Prodigy heats both the mobile phase and column to a uniform temperature, enabling high efficiency chromatography while allowing routine access to greener, higher-viscosity solvents such as ethanol.

· Elevated Temperature Chromatography
Excellent separation of hydrophobic peptides.
Elevated temperatures increase the solubility of hydrophobic peptides, improving peak shape and resolution. This results in higher fraction purities and recoveries, while minimizing the number of fractions.

· Chromatographic Selectivity
Resolve more impurities.
Temperature is an important parameter that can affect chromatographic selectivity. With the Prodigy, you can maximize your ability to resolve closely eluting impurities.

· Workflow Solution
No more ambient temperature scouting runs.
Conventional ambient temperature purification workflows often require additional scouting runs. With the Prodigy, elevated temperature analytical runs can be performed directly at the preparative scale.

· Productivity
Run the fastest, most optimized methods.
The use of elevated temperatures results in improved mass transfer kinetics and reduced system backpressure. This enables much higher flow rates and shorter run times.

· The built-in focused gradient calculator makes it easy to create optimized focused gradients, minimizing run time while maximizing resolution around the target peak.

· Intuitive Software
User-friendly software, scientist centered design.
The touchscreen software interface enables the fast, easy, and efficient operation of the system.
Features
· Complete elimination of acetonitrile
· Elevated temperature chromatography
· Intuitive touchscreen software interface
· 5-position autosampler
· Excellent separation of hydrophobic peptides
· Injections up to 500 mg
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