Medium Fiber Cartridges for Cell Culture

Medium Polysulfone Fiber Cartridge (5kD MWCO):
Low MWCO (5 kD @ 50%) hydrophilic polysulfone fiber for recombinant proteins between 25 kD and 100 kD. Appropriate for adherent and suspension cell lines including CHO, HeLa and 293. Can support up to 10^9 cells and produce 100 µg/mL/day or more of recombinant protein in 20 mL ECS.

Medium Polysulfone Fiber Cartridge (20kD MWCO):
High MWCO (20 kD @ 50%) hydrophilic polysulfone fiber for monoclonal antibodies and larger recombinant proteins (100 kD or larger). Can support up to 10^9 cells and produce 1-5 mg of a recombinant protein every day or 5-100 mg of a monoclonal antibody every other day. This is the cartridge of choice for PK/PD studies.

HI Output Mab, High Flux Polysulfone Fiber Cartridge (20kD MWCO):
The C5011 is the same cartridge as the C2011 but with twice the oxygenation capacity. It is specifically designed for hybridoma scale-up with 2X greater productivity and twice the antibody concentration of the C2011.

Medium Cellulosic Fiber Cartridge (12kD MWCO):
Cellulosic cartridge with 12.5 kD MWCO. Cellulosic fibers are solvent resistant and may offer lower non-specific binding to non-polar drugs than the polysulfone fiber.