Liberty PRIME 2.0 Microwave Peptide Synthesizer

· Ultra Efficient - Solid Phase Peptide Synthesis (UE-SPPS)
New "No Wash" approach, same clean peptides.
With this Liberty system comes the revolutionary UE-SPPS methodology; total wash elimination. Through a remarkable combination of methodology optimization, reagent selection, and engineering advancements, "No Wash" technology reduces waste production by up to 95%, and all without sacrificing synthesis yield and purity.

· Unmatched Peptide Quality
A new level of peptide purity.
With advancements in system fluidics, reaction vessel environment, and chemistry methodology achieve better synthesis results than ever before.

· Better Chemistry
Carbodiimide coupling strategy for reduced epimerization and side reactions
ProTide resin development for optimized loading and swelling parameters
Microwave heating approach for improved reaction efficiency and synthesis results
Better Engineering
Headspace flushing technology for cleaner reaction environment
Optimized flow paths for simple and efficient reagent delivery
Digitally variable N₂ control for enhanced bubbling, purging, and draining

· Advanced Reagent Delivery System
The best way to deliver critical reagents.
All reagents are delivered either by pressure-based Flex-Add™ delivery system or precalibrated pumping system.

· No volume constraints for infinitely variable delivery quantities, unlike sample loops
No calibrations for calibration-free reagent delivery ideal for cGMP processes
Never prime amino acids - avoid unnecessary consumption of expensive and precious reagents
No washing for elegant flow path design eliminates waste from background cleaning steps

· High Throughput (HT) Loaders
More peptide synthesis, less hands-on time.
Queue up to 4 sequential syntheses with the optional HT4 accessory, up to 12 sequential syntheses with the HT12, and up to 24 sequential syntheses with the HT24.

· Each peptide is available immediately, eliminating purification bottlenecks common with batch syntheses.

· <4 minute per amino acid (AA) addition (includes coupling through deprotection, scales under 0.5 mmol)
· <5 mL waste generated per AA addition (includes coupling through deprotection, scales under 0.2 mmol )
· 0.005 to 5 mmol synthesis scale range
· HT accessories available for queueing up to 24 syntheses
· cGMP peptide production compliant package available