DN66PC/N66PC Sterilizing-Grade Liquid Filter

Cat. No. Specification Unit Price Quantity
FCM1504298-01 Membrane: Nylon 66 each Inquiry

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Product Description
Product Description
DN66PC/N66PC series filter cartridges are made of naturally hydrophilic nylon 66 membranes, which are modified with positively-charged N66 membranes to absorb and remove particles, bacteria and endotoxins that are smaller than the filter pore size.

Quality:
· 100% Integrity testing in manufacturing
· Each filter is fully traceable with unique serial number
· Manufactured in a facility which adheres to ISO 9001:2015 Practices
Features
· Naturally hydrophilic
· The use of modified positively-charged N66 membranes removes endotoxins from water, absorbing particles and endotoxins smaller than the filter membrane pore size.
· Good integrity and high bubble point values ensure excellent sterilization and particle removal efficiency
· Low pressure drop, high flow rates, long-life
Specifications

Materials of Construction

Membrane Nylon 66
Support Polypropylene (PP), polyester (PET)
Core/Cage/End Caps Polypropylene (PP)
End Cap Inserts Polybutylene terephthalate (PBT)
Seal Material Silicone / EPDM / Viton
FEP/ PFA encapsulated O-rings


Operating Conditions

Max. Operating Temperature
80°C
Max.Operating Pressure
0.69 MPa@25°C
0.40 MPa@60°C
0.24 MPa@80°C
Max. Differential Pressure (Forward)
0.69 MPa@25°C
0.40 MPa@60°C
0.24 MPa@80°C
Max. Differential Pressure (Reverse)
0.30 MPa@25°C
0.10 MPa@80°C


Filtration Area

Outer Diameter Membrane Pore Size Area/10'
DN66PC 69 mm 0.22+0.22 μm 0.58 m²
69 mm 0.45+0.22 μm 0.68 m²
71 mm 0.45+0.22 μm 0.82 m²
69 mm 1.2+0.45 μm 0.84 m²
N66PC 69 mm 0.22 μm 0.65 m²


Integrity Test Standards @10inch, 20°C (DN66PC)

Membrane Pore Size Bubble Point Air Diffusion
0.22+0.22 μm ≥ 0.30 MPa (water), Air test ≤ 16 ml/min @ 0.275 MPa (water)
0.45+0.22 μm(outer diameter 69mm) ≥ 0.30 MPa (water), Air test ≤ 20 ml/min @ 0.275 MPa (water)
0.45+0.22 μm(outer diameter 71mm) ≥ 0.30 MPa (water), Air test ≤ 24 ml/min @ 0.275 MPa (water)
1.2+0.45 μm ≥ 0.12 MPa (water), Air test ≤ 18 ml/min @ 0.1 MPa (water)


Integrity Test Standards @10inch, 20°C (N66PC)

Membrane Pore Size Bubble Point Air Diffusion
0.22 μm ≥ 0.30 MPa, Wetted with water, Air test /


Bacterial Retention

Model Content
69DN66PC 0.22+0.22 μm Bacterial quantitative retention of 10⁷ cfu/cm² Brevundimonas diminuta (ATCC 19146) accordingto ASTM F838 methodology.
69DN66PC 0.45+0.22 μm
71DN66PC 0.45+0.22 μm
69DN66PC 1.2+0.45 μm Bacterial quantitative retention of 10⁷ cfu/cm² Serratia marcescens (ATCC14756) according to ASTM F838 methodology
N66PC 0.22 μm Bacterial quantitative retention of 10⁷ cfu/cm² Brevundimonas diminuta (ATCC 19146) accordingto ASTM F838 methodology.


Sterilization

In-line steam sterilization Up to 10 cycles (121°C for 30 minutes and differential pressure <30KPa per cycle )


Regulatory Compliance

  • Autoclaved filter effluent meets the USP<788> requirement of particulate matter in large volume injection.
  • Component materials meet the criteria for a' Non-fiber-releasing filter' as defined in 21 CFR 210.3(b)(6).
  • Aqueous extraction from a cartridge contains less than 0.25EU/ml as determined by Limulus Amebocyte Lysate (LAL), meeting requirements of USP<85>.
  • Meet the requirement of USP <87> In Vitro Cytotoxicity Test.
  • Component materials meet the requirements of the current USP<88> for plastic class VI-121°C.
  • All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182.
  • Based on the current information from our suppliers, all component materials used in the manufacture of this product are animal-free.
Ordering Information:

DN66PC (Double-layer)

Outer Diameter Type Membrane Pore Size End Cap Nominal Length Seal Material Industry
   69mm DN66PC 0022   0.22 µm DOE   Double Open End 05   5 inch S   Silicone P
71   71mm 2222   0.22+0.22 µm HTF   222/Fin (PBT insert) 10   10 inch E   EPDM
4522   0.45+0.22 µm HSF   226/Fin (PBT insert) 20   20 inch V   Viton
1245   1.2+0.45 µm HTCG   222/Flat (PBT insert) 30   30 inch P   FEP/PFA encapsulated O-rings

HSCG   226/Flat (PBT insert) 40   40 inch


N66PC (Single-layer)

Outer Diameter Type Membrane Pore Size End Cap Nominal Length Seal Material Industry
   69mm N66PC 0022   0.22 µm DOE   Double Open End 05   5 inch S   Silicone P
71   71mm
0045   0.45 μm HTF   222/Fin (PBT insert) 10   10 inch E   EPDM

0120   1.2 μm HSF   226/Fin (PBT insert) 20   20 inch V   Viton


HTCG   222/Flat (PBT insert) 30   30 inch P   FEP/PFA encapsulated O-rings

HSCG   226/Flat (PBT insert) 40   40 inch


* Example: DN66PC2222DOE05SP (DN66PC, 0.22+0.22µm, Double open end, 5 inch, Silicone, Pharmaceutical)
Applications
Application Description
Sterile filtration for LVP, SVP and antibiotic solutions
Sterile filtration of saline and other solvents
Filtration of pharmaceutical water and removal of pyrogens
Pharmaceutical sterile filtration
Solvent filtration
Alkaline solution filtration
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