Anti-IL2RA Monoclonal Antibody (Basiliximab)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Price	Availability
ASPC010	Anti-IL2RA Antibody (Basiliximab)	Human IgG1, Kappa		None	$460	4-6 weeks	Add
ASPC010-P	Anti-IL2RA Antibody (Basiliximab), PE	Human IgG1, Kappa		PE	$1,180	2-3 weeks	Add
ASPC010-A	Anti-IL2RA Antibody (Basiliximab), APC	Human IgG1, Kappa		APC	$980	2-3 weeks	Add
ASPC010-H	Anti-IL2RA Antibody (Basiliximab), HRP	Human IgG1, Kappa		HRP	$600	2-3 weeks	Add
ASPC010-B	Anti-IL2RA Antibody (Basiliximab), Biotin	Human IgG1, Kappa		Biotin	$680	2-3 weeks	Add
ASPC010-3	Anti-IL2RA Antibody (Basiliximab), Non-fucosylated	Human IgG1, Kappa	Non-fucosylated	None	$980	In stock	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC010

Anti-IL2RA Antibody (Basiliximab)

Human IgG1, Kappa

None

$460

4-6 weeks

Add

ASPC010-P

Anti-IL2RA Antibody (Basiliximab), PE

Human IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC010-A

Anti-IL2RA Antibody (Basiliximab), APC

Human IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC010-H

Anti-IL2RA Antibody (Basiliximab), HRP

Human IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC010-B

Anti-IL2RA Antibody (Basiliximab), Biotin

Human IgG1, Kappa

Biotin

$680

2-3 weeks

Add

ASPC010-3

Anti-IL2RA Antibody (Basiliximab), Non-fucosylated

Human IgG1, Kappa

Non-fucosylated

None

$980

In stock

Add

Anti-IL2RA Monoclonal Antibody (Basiliximab)
- Product Description:
  
  Basiliximab is a chimeric mouse-human monoclonal antibody. Basiliximab targets the alpha chain (CD25) of the interleukin-2 (IL-2) receptor on the surface of activated T-lymphocytes. Generally, the binding of basiliximab to CD25 inhibits the receptor’s interaction with IL-2, preventing downstream signaling required for T-cell activation.
  
  Applications:
  
  Western Blot, Blocking, Flow Cytometry, Immunofluorescence, Immunohistochemistry
  
  Source:
  
  Mouse
  
  Target:
  
  IL2RA
  
  Specificity:
  
  Humna interleukin-2 receptor alpha chain
  
  Immunogen:
  
  CTC 16 cells
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  Basiliximab
  
  Isotype:
  
  Human IgG1, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-IL2RA Monoclonal Antibody (Basiliximab) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

IL2RA

Protein Name

Interleukin-2 receptor subunit alpha

Molecular Family

CD Molecules, Cytokine/Chemokine Receptors

Introduction

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.

Alternative Names

Interleukin 2 Receptor Subunit Alpha; IL2RA

Gene ID

3559

UniProt

P01589

Related Disease

Type 1 diabetes mellitus 10 (T1D10)

Cell Type

Dendritic cells, Macrophages, Monocytes, T cells, Thymocytes, Tregs

Function

Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

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