Anti-HLA-DR Monoclonal Antibody - Amerigo Scientific

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC799	Anti-HLA-DR Antibody	Human IgG4, Kappa	None	$460	In stock	Add
ASPC799-P	Anti-HLA-DR Antibody, PE	Human IgG4, Kappa	PE	$1,180	2-3 weeks	Add
ASPC799-A	Anti-HLA-DR Antibody, APC	Human IgG4, Kappa	APC	$980	2-3 weeks	Add
ASPC799-H	Anti-HLA-DR Antibody, HRP	Human IgG4, Kappa	HRP	$600	2-3 weeks	Add
ASPC799-B	Anti-HLA-DR Antibody, Biotin	Human IgG4, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC799

Anti-HLA-DR Antibody

Human IgG4, Kappa

None

$460

In stock

Add

ASPC799-P

Anti-HLA-DR Antibody, PE

Human IgG4, Kappa

$1,180

2-3 weeks

Add

ASPC799-A

Anti-HLA-DR Antibody, APC

Human IgG4, Kappa

APC

$980

2-3 weeks

Add

ASPC799-H

Anti-HLA-DR Antibody, HRP

Human IgG4, Kappa

HRP

$600

2-3 weeks

Add

ASPC799-B

Anti-HLA-DR Antibody, Biotin

Human IgG4, Kappa

Biotin

$680

2-3 weeks

Add

Anti-HLA-DR Monoclonal Antibody
- Product Description:
  
  The Anti-HLA-DR antibody is a human monoclonal antibody recommended for use in flow cytometry, functional assay and other applications. This antibody specifically targets HLA-DR and demonstrates reactivity with human.
  
  Applications:
  
  Flow Cytometry, Functional Assay
  
  Target:
  
  HLA-DR
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human HLA-DR.
  
  Clonality:
  
  Monoclonal
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-HLA-DR Monoclonal Antibody Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Introduction

HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. This molecule is expressed on the surface of various antigen presenting cells such as B lymphocytes, dendritic cells, and monocytes/macrophages, and plays a central role in the immune system and response by presenting peptides derived from extracellular proteins, in particular, pathogen-derived peptides to T cells. The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.

Alternative Names

HLA-DRA1; HLA class II; HLA class II histocompatibility antigen; Histocompatibility antigen HLA-DR alpha

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