Anti-TIGIT Monoclonal Antibody (13H6)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC825	Anti-TIGIT Antibody (13H6)	Human IgG1, Kappa	None	$460	In stock	Add
ASPC825-P	Anti-TIGIT Antibody (13H6), PE	Human IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC825-A	Anti-TIGIT Antibody (13H6), APC	Human IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC825-H	Anti-TIGIT Antibody (13H6), HRP	Human IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC825-B	Anti-TIGIT Antibody (13H6), Biotin	Human IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC825

Anti-TIGIT Antibody (13H6)

Human IgG1, Kappa

None

$460

In stock

Add

ASPC825-P

Anti-TIGIT Antibody (13H6), PE

Human IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC825-A

Anti-TIGIT Antibody (13H6), APC

Human IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC825-H

Anti-TIGIT Antibody (13H6), HRP

Human IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC825-B

Anti-TIGIT Antibody (13H6), Biotin

Human IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-TIGIT Monoclonal Antibody (13H6)
- Product Description:
  
  The Anti-TIGIT antibody is a human monoclonal antibody recommended for use in ELISA, flow cytometry, blocking and other applications. This antibody specifically targets TIGIT and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Blocking, Western Blot
  
  Target:
  
  TIGIT
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human TIGIT.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  13H6
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-TIGIT Monoclonal Antibody (13H6) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

TIGIT

Protein Name

T-cell immunoreceptor with Ig and ITIM domains

Introduction

This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.

Alternative Names

VSIG9; VSTM3; WUCAM

Gene ID

201633

UniProt

Q495A1

Molecule Mass

Adhesion Molecules, Immune Checkpoint Receptors

Subcellular Location

Cell membrane

Tissue Specificity

Expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells (at protein level).

Cell Line Specificity

Group enriched

Function

Inhibitory receptor that plays a role in the modulation of immune responses. Suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.

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