Full Name: SIVA1 Apoptosis Inducing Factor
BACKGROUND: This gene encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. The CD27 antigen cytoplasmic tail binds to the N-terminus of this protein. Two alternatively spliced transcript variants encoding distinct proteins have been described.
Synonyms: CD27BP; SIVA; Siva-1; Siva-2
Research Areas: Cell Biology
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