Anti-Reovirus type 3 Sigma1 Monoclonal Antibody (9BG5)

Subcat	Description	Isotype	Conjugate	Price
ASPC1337	Anti-Reovirus type 3 Sigma1 Antibody (9BG5)	Mouse IgG2a, Kappa	None	$460	Add
ASPC1337-A	Anti-Reovirus type 3 Sigma1 Antibody (9BG5), APC	Mouse IgG2a, Kappa	APC	$980	Add
ASPC1337-B	Anti-Reovirus type 3 Sigma1 Antibody (9BG5), Biotin	Mouse IgG2a, Kappa	Biotin	$680	Add
ASPC1337-H	Anti-Reovirus type 3 Sigma1 Antibody (9BG5), HRP	Mouse IgG2a, Kappa	HRP	$600	Add
ASPC1337-P	Anti-Reovirus type 3 Sigma1 Antibody (9BG5), PE	Mouse IgG2a, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC1337

Anti-Reovirus type 3 Sigma1 Antibody (9BG5)

Mouse IgG2a, Kappa

None

$460

Add

ASPC1337-A

Anti-Reovirus type 3 Sigma1 Antibody (9BG5), APC

Mouse IgG2a, Kappa

APC

$980

Add

ASPC1337-B

Anti-Reovirus type 3 Sigma1 Antibody (9BG5), Biotin

Mouse IgG2a, Kappa

Biotin

$680

Add

ASPC1337-H

Anti-Reovirus type 3 Sigma1 Antibody (9BG5), HRP

Mouse IgG2a, Kappa

HRP

$600

Add

ASPC1337-P

Anti-Reovirus type 3 Sigma1 Antibody (9BG5), PE

Mouse IgG2a, Kappa

$1,180

Add

Anti-Reovirus type 3 Sigma1 Monoclonal Antibody (9BG5)
- Product Description:
  
  The Anti-Reovirus type 3 Sigma1 antibody is a mouse monoclonal antibody recommended for use in flow cytometry, radioimmunoassay, immunoprecipitation and other applications. This antibody specifically targets Reovirus type 3 Sigma1.
  
  Applications:
  
  Flow Cytometry, Radioimmunoassay, Immunoprecipitation
  
  Target:
  
  Reovirus type 3 Sigma1
  
  Specificity:
  
  This antibody reacts with Reovirus type 3 Sigma1.
  
  Immunogen:
  
  Reovirus T3D
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  9BG5
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-Reovirus type 3 Sigma1 Monoclonal Antibody (9BG5) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

Protein Name

Outer capsid protein sigma-1

Introduction

The sigma 1 (σ1) protein is an outer capsid protein of Reovirus type 3. It acts as the viral attachment protein, binding to specific receptors on host cells (such as the junctional adhesion molecule-1, JAM-1). This interaction determines viral tropism and is important for pathogenesis.

Alternative Names

S1; Outer capsid protein sigma-1; Sigma1; Cell attachment protein; Hemagglutinin

UniProt

P03528

Subcellular Location

Virion.

Function

Fiber-like molecule that attaches the virion to the host cell membrane by binding to the primary receptor F11R/JAM-A and to sialic acid containing proteins (coreceptor). The interaction of sigma-1 with F11R is required for NF-kB activation and apoptosis. Binding to both sialic acid and F11R is required to induce maximal levels of apoptosis.

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