Anti-JAG1 Monoclonal Antibody (12F11)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC419	Anti-JAG1 Antibody (12F11)	Human IgG1, Kappa	None	$460	In stock	Add
ASPC419-P	Anti-JAG1 Antibody (12F11), PE	Human IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC419-A	Anti-JAG1 Antibody (12F11), APC	Human IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC419-H	Anti-JAG1 Antibody (12F11), HRP	Human IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC419-B	Anti-JAG1 Antibody (12F11), Biotin	Human IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC419

Anti-JAG1 Antibody (12F11)

Human IgG1, Kappa

None

$460

In stock

Add

ASPC419-P

Anti-JAG1 Antibody (12F11), PE

Human IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC419-A

Anti-JAG1 Antibody (12F11), APC

Human IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC419-H

Anti-JAG1 Antibody (12F11), HRP

Human IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC419-B

Anti-JAG1 Antibody (12F11), Biotin

Human IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-JAG1 Monoclonal Antibody (12F11)
- Product Description:
  
  The Anti-JAG1 antibody is a human monoclonal antibody recommended for use in ELISA and other applications. This antibody specifically targets JAG1 and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay
  
  Target:
  
  JAG1
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Jagged 1.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  12F11
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-JAG1 Monoclonal Antibody (12F11) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

JAG1

Protein Name

Protein jagged-1

Introduction

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Alternative Names

AGS; AHD; AWS; HJ1; AGS1; CD339; JAGL1

Gene ID

182

UniProt

P78504

Molecule Mass

CD Molecules

Related Disease

Alagille syndrome 1 (ALGS1)

Subcellular Location

Membrane; Single-pass type I membrane protein. Cell membrane

Cell Line Specificity

Low cancer specificity

Function

Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro).

Customer Reviews

There are no reviews for Product Name.

Submit a review and receive an Amazon gift card.

Publications

There are no publications for Product Name.

If you couldn't find the specific publication, you can:
Submit a Citation Get a Publication Reward