Anti-FCER2 Monoclonal Antibody (Lumiliximab)

Subcat	Description	Isotype	Conjugate	Price
ASPC1083	Anti-FCER2 Antibody (Lumiliximab)	Human IgG1, Kappa	None	$460	Add
ASPC1083-A	Anti-FCER2 Antibody (Lumiliximab), APC	Human IgG1, Kappa	APC	$980	Add
ASPC1083-B	Anti-FCER2 Antibody (Lumiliximab), Biotin	Human IgG1, Kappa	Biotin	$680	Add
ASPC1083-H	Anti-FCER2 Antibody (Lumiliximab), HRP	Human IgG1, Kappa	HRP	$600	Add
ASPC1083-P	Anti-FCER2 Antibody (Lumiliximab), PE	Human IgG1, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC1083

Anti-FCER2 Antibody (Lumiliximab)

Human IgG1, Kappa

None

$460

Add

ASPC1083-A

Anti-FCER2 Antibody (Lumiliximab), APC

Human IgG1, Kappa

APC

$980

Add

ASPC1083-B

Anti-FCER2 Antibody (Lumiliximab), Biotin

Human IgG1, Kappa

Biotin

$680

Add

ASPC1083-H

Anti-FCER2 Antibody (Lumiliximab), HRP

Human IgG1, Kappa

HRP

$600

Add

ASPC1083-P

Anti-FCER2 Antibody (Lumiliximab), PE

Human IgG1, Kappa

$1,180

Add

Anti-FCER2 Monoclonal Antibody (Lumiliximab)
- Product Description:
  
  The Anti-FCER2 antibody is a human monoclonal antibody recommended for use in immunoprecipitation, functional assay, flow cytometry and other applications. This antibody specifically targets FCER2 and demonstrates reactivity with human.
  
  Applications:
  
  Immunoprecipitation, Functional Assay, Flow Cytometry
  
  Target:
  
  FCER2
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with Human FCER2.
  
  Immunogen:
  
  Human CD23 antigen.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  Lumiliximab
  
  Clone Synonyms:
  
  IDEC-152
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-FCER2 Monoclonal Antibody (Lumiliximab) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

FCER2

Protein Name

Low affinity immunoglobulin epsilon Fc receptor

Introduction

The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Alternative Names

BLAST-2; CD23; CD23A; CLEC4J; FCE2; IGEBF

Gene ID

2208

UniProt

P06734

Tissue Specificity

Detected in urine (at protein level).

Cell Line Specificity

Group enriched

Function

Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway.

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