Anti-DSG2 Monoclonal Antibody (10F8)

Anti-DSG2 Monoclonal Antibody (10F8)

Cat No: ASPC719

Summary
Host Species:
Human
Species Reactivity:
Human
Applications:
Flow Cytometry, Immunoprecipitation
Clone ID:
10F8
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Quantity
ASPC719 Anti-DSG2 Antibody (10F8) Human IgG1, Kappa None $460
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ASPC719-P Anti-DSG2 Antibody (10F8), PE Human IgG1, Kappa PE $1,180
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ASPC719-A Anti-DSG2 Antibody (10F8), APC Human IgG1, Kappa APC $980
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ASPC719-H Anti-DSG2 Antibody (10F8), HRP Human IgG1, Kappa HRP $600
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ASPC719-B Anti-DSG2 Antibody (10F8), Biotin Human IgG1, Kappa Biotin $680
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-DSG2 Monoclonal Antibody (10F8)
    • Product Description:
      The Anti-DSG2 antibody is a human monoclonal antibody recommended for use in flow cytometry, immunoprecipitation and other applications. This antibody specifically targets DSG2 and demonstrates reactivity with human.
      Applications:
      Flow Cytometry, Immunoprecipitation
      Target:
      DSG2
      Target Species:
      Human
      Specificity:
      This antibody reacts with human DSG2.
      Clonality:
      Monoclonal
      Clone ID:
      10F8
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-DSG2 Monoclonal Antibody (10F8) Applications
    • Note:
      Optimal dilutions/concentrations should be determined by the end user.
Gene Symbol
DSG2
Protein Name
Desmoglein-2
Introduction
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein.
Alternative Names
Desmoglein 2; Cadherin Family Member 5; CDHF5; HDGC; Desmoglein-2
Gene ID
UniProt
Molecule Mass
Adhesion Molecules
Related Disease
Arrhythmogenic right ventricular dysplasia, familial, 10 (ARVD10)
Subcellular Location
Cell membrane
Tissue Specificity
All of the tissues tested and carcinomas.
Cell Line Specificity
Low cancer specificity
Function
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
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