Anti-VTCN1 Monoclonal Antibody (5B9)

Anti-VTCN1 Monoclonal Antibody (5B9)

Cat No: ASPC292

Summary
Host Species:
Mouse
Species Reactivity:
Human
Applications:
Enzyme-Linked Immunosorbent Assay, Flow Cytometry
Clone ID:
5B9
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Availability Quantity
ASPC292 Anti-VTCN1 Antibody (5B9) Mouse IgG1, Kappa None $460 In stock
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ASPC292-P Anti-VTCN1 Antibody (5B9), PE Mouse IgG1, Kappa PE $1,180 2-3 weeks
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ASPC292-A Anti-VTCN1 Antibody (5B9), APC Mouse IgG1, Kappa APC $980 2-3 weeks
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ASPC292-H Anti-VTCN1 Antibody (5B9), HRP Mouse IgG1, Kappa HRP $600 2-3 weeks
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ASPC292-B Anti-VTCN1 Antibody (5B9), Biotin Mouse IgG1, Kappa Biotin $680 2-3 weeks
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-VTCN1 Monoclonal Antibody (5B9)
    • Product Description:
      The Anti-VTCN1 antibody is a mouse monoclonal antibody recommended for use in ELISA, flow cytometry and other applications. This antibody specifically targets VTCN1 and demonstrates reactivity with human.
      Applications:
      Enzyme-Linked Immunosorbent Assay, Flow Cytometry
      Target:
      VTCN1
      Target Species:
      Human
      Specificity:
      This antibody reacts with human B7-H4.
      Immunogen:
      Human VTCN1 protein
      Clonality:
      Monoclonal
      Clone ID:
      5B9
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-VTCN1 Monoclonal Antibody (5B9) Applications
    • Note:
      Optimal dilutions/concentrations should be determined by the end user.
Gene Symbol
VTCN1
Protein Name
V-set domain-containing T-cell activation inhibitor 1
Introduction
This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression.
Alternative Names
VTCN1; V-set domain containing T cell activation inhibitor 1; B7X; B7H4; B7S1; B7-H4; B7h. 5; VCTN1; PRO129
Gene ID
UniProt
Subcellular Location
Cell membrane
Cell Line Specificity
Cancer enhanced
Function
Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
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