Anti-TNF Monoclonal Antibody (D2E7)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC037	Anti-TNF Antibody (D2E7)	Human IgG1, Kappa	None	$460	In stock	Add
ASPC037-P	Anti-TNF Antibody (D2E7), PE	Human IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC037-A	Anti-TNF Antibody (D2E7), APC	Human IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC037-H	Anti-TNF Antibody (D2E7), HRP	Human IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC037-B	Anti-TNF Antibody (D2E7), Biotin	Human IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC037

Anti-TNF Antibody (D2E7)

Human IgG1, Kappa

None

$460

In stock

Add

ASPC037-P

Anti-TNF Antibody (D2E7), PE

Human IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC037-A

Anti-TNF Antibody (D2E7), APC

Human IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC037-H

Anti-TNF Antibody (D2E7), HRP

Human IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC037-B

Anti-TNF Antibody (D2E7), Biotin

Human IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-TNF Monoclonal Antibody (D2E7)
- Product Description:
  
  D2E7 is a monoclonal antibody that specifically targets and neutralizes tumor necrosis factor-alpha (TNF-α), a cytokine involved in systemic inflammation. It was created using phage display technology and is classified as a human IgG1 antibody.
  
  Applications:
  
  Blocking, Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry
  
  Target:
  
  TNF
  
  Specificity:
  
  Soluble TNF-alpha
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  D2E7
  
  Isotype:
  
  Human IgG1, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-TNF Monoclonal Antibody (D2E7) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

TNF

Protein Name

Tumor necrosis factor

Molecular Family

Cytokines/Chemokines

Introduction

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Alternative Names

Tumor Necrosis Factor; Tumor Necrosis Factor Ligand Superfamily Member 2; Cachectin; TNF-Alpha; TNFSF2; TNF-A; TNFA; Tumor Necrosis Factor (TNF Superfamily, Member 2); Tumor Necrosis Factor Ligand 1F

Gene ID

7124

UniProt

P01375

Cell Type

Tregs

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