Anti-LASV GPC Monoclonal Antibody (37.7H)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Price	Availability
ASPC055	Anti-LASV GPC Antibody (37.7H)	Human IgG1, Lambda		None	$460	In stock	Add
ASPC055-P	Anti-LASV GPC Antibody (37.7H), PE	Human IgG1, Lambda		PE	$1,180	2-3 weeks	Add
ASPC055-A	Anti-LASV GPC Antibody (37.7H), APC	Human IgG1, Lambda		APC	$980	2-3 weeks	Add
ASPC055-H	Anti-LASV GPC Antibody (37.7H), HRP	Human IgG1, Lambda		HRP	$600	2-3 weeks	Add
ASPC055-B	Anti-LASV GPC Antibody (37.7H), Biotin	Human IgG1, Lambda		Biotin	$680	2-3 weeks	Add
ASPC055-4	Anti-LASV GPC Antibody (37.7H), Fc Silenced	Human IgG1, Lambda	Fc Silenced	None	$980	4-6 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC055

Anti-LASV GPC Antibody (37.7H)

Human IgG1, Lambda

None

$460

In stock

Add

ASPC055-P

Anti-LASV GPC Antibody (37.7H), PE

Human IgG1, Lambda

$1,180

2-3 weeks

Add

ASPC055-A

Anti-LASV GPC Antibody (37.7H), APC

Human IgG1, Lambda

APC

$980

2-3 weeks

Add

ASPC055-H

Anti-LASV GPC Antibody (37.7H), HRP

Human IgG1, Lambda

HRP

$600

2-3 weeks

Add

ASPC055-B

Anti-LASV GPC Antibody (37.7H), Biotin

Human IgG1, Lambda

Biotin

$680

2-3 weeks

Add

ASPC055-4

Anti-LASV GPC Antibody (37.7H), Fc Silenced

Human IgG1, Lambda

Fc Silenced

None

$980

4-6 weeks

Add

Anti-LASV GPC Monoclonal Antibody (37.7H)
- Product Description:
  
  The 37.7H antibody is a monoclonal antibody that reacts with the Lassa virus glycoprotein. This specific binding can neutralize the virus by blocking the conformational changes necessary for viral entry into host cells.
  
  Applications:
  
  Neutralization, Enzyme-Linked Immunosorbent Assay, Western Blot
  
  Source:
  
  Human
  
  Target:
  
  LASV GPC
  
  Target Species:
  
  Lassa Virus
  
  Specificity:
  
  Lassa virus glycoprotein
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  37.7H
  
  Isotype:
  
  Human IgG1, Lambda
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-LASV GPC Monoclonal Antibody (37.7H) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

GPC

Protein Name

Pre-glycoprotein polyprotein GP complex

Introduction

The glycoprotein complex (GPC) is the only viral protein on the surface of LASV and presents the sole target for neutralizing antibodies (NAbs).The GPC is expressed as a single polypeptide precursor before being proteolytically processed by signal peptidase (SPase) followed by site-1 protease (S1P). In its mature, native form, GPC is a trimer of heterotrimers comprised of the receptor-engaging subunit GP1; the transmembrane-spanning subunit GP2, which contains the GPC’s fusion peptide at its N terminus; and the stable signal peptide (SSP), which remains non-covalently complexed near the membrane-proximal region of GP2 post-cleavage.

Alternative Names

GPC; LASV GPC; Glycoprotein Complex; Pre-glycoprotein polyprotein GP complex

UniProt

P08669

Cell Type

B cells, Dendritic cells, T cells, Thymocytes

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