Anti-Gb3 Monoclonal Antibody (14A6)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC831	Anti-Gb3 Antibody (14A6)	Human IgG1, Kappa	None	$460	In stock	Add
ASPC831-P	Anti-Gb3 Antibody (14A6), PE	Human IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC831-A	Anti-Gb3 Antibody (14A6), APC	Human IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC831-H	Anti-Gb3 Antibody (14A6), HRP	Human IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC831-B	Anti-Gb3 Antibody (14A6), Biotin	Human IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC831

Anti-Gb3 Antibody (14A6)

Human IgG1, Kappa

None

$460

In stock

Add

ASPC831-P

Anti-Gb3 Antibody (14A6), PE

Human IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC831-A

Anti-Gb3 Antibody (14A6), APC

Human IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC831-H

Anti-Gb3 Antibody (14A6), HRP

Human IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC831-B

Anti-Gb3 Antibody (14A6), Biotin

Human IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-Gb3 Monoclonal Antibody (14A6)
- Product Description:
  
  The Anti-Gb3 antibody is a human monoclonal antibody recommended for use in ELISA, flow cytometry and other applications. This antibody specifically targets Gb3.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Flow Cytometry
  
  Target:
  
  Gb3
  
  Specificity:
  
  This antibody reacts with Gb3.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  14A6
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-Gb3 Monoclonal Antibody (14A6) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Introduction

Globotriaosylceramide is a ganglioside. It is also known as CD77, Gb3, and ceramide trihexoside. It is one of the few clusters of differentiation that is not a protein. It is formed by the alpha linkage of galactose to lactosylceramide catalyzed by A4GALT. It is metabolized by alpha-galactosidase, which hydrolyzes the terminal alpha linkage. Defects in the enzyme alpha-galactosidase lead to the build up of globotriaosylceramide, causing Fabry's disease. Globotriaosylceramide is also one of the targets of Shiga toxin, which is responsible for pathogenicity of enterohemorrhagic Escherichia coli (EHEC).

Alternative Names

Gb3; Glycosphingolipid globotriaosylceramide; CD77

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