Anti-EPHA3 Monoclonal Antibody - Amerigo Scientific

Subcat	Description	Isotype	Conjugate	Price
ASPC091	Anti-EPHA3 Monoclonal Antibody	Human IgG1, Kappa	None	$460	Add
ASPC091-P	Anti-EPHA3 Monoclonal Antibody, PE	Human IgG1, Kappa	PE	$1,180	Add
ASPC091-A	Anti-EPHA3 Monoclonal Antibody, APC	Human IgG1, Kappa	APC	$980	Add
ASPC091-H	Anti-EPHA3 Monoclonal Antibody, HRP	Human IgG1, Kappa	HRP	$600	Add
ASPC091-B	Anti-EPHA3 Monoclonal Antibody, Biotin	Human IgG1, Kappa	Biotin	$680	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC091

Anti-EPHA3 Monoclonal Antibody

Human IgG1, Kappa

None

$460

Add

ASPC091-P

Anti-EPHA3 Monoclonal Antibody, PE

Human IgG1, Kappa

$1,180

Add

ASPC091-A

Anti-EPHA3 Monoclonal Antibody, APC

Human IgG1, Kappa

APC

$980

Add

ASPC091-H

Anti-EPHA3 Monoclonal Antibody, HRP

Human IgG1, Kappa

HRP

$600

Add

ASPC091-B

Anti-EPHA3 Monoclonal Antibody, Biotin

Human IgG1, Kappa

Biotin

$680

Add

Anti-EPHA3 Monoclonal Antibody
- Product Description:
  
  This antibody is a recombinant, IgG1κ monoclonal antibody specifically designed to target EphA3, a member of the Ephrin receptor tyrosine kinase family. EphA3 is overexpressed in various hematologic malignancies and solid tumors, making it a promising target for cancer therapy.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Functional Assay
  
  Target:
  
  EPHA3
  
  Target Species:
  
  Human
  
  Specificity:
  
  Human EPHA3
  
  Immunogen:
  
  LK63 cell line
  
  Clonality:
  
  Monoclonal
  
  Isotype:
  
  Human IgG1, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-EPHA3 Monoclonal Antibody Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

EPHA3

Protein Name

Ephrin type-A receptor 3

Introduction

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.

Alternative Names

EPH Receptor A3; Tyrosine-Protein Kinase Receptor ETK1; Eph-Like Tyrosine Kinase 1; EPH-Like Kinase 4; EC 2.7.10.1; TYRO4; HEK4; ETK1; ETK; EK4

Gene ID

2042

UniProt

P29320

Related Disease

Colorectal cancer (CRC)

Subcellular Location

Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol

Tissue Specificity

Widely expressed. Highest level in placenta.