Anti-AGR2 Monoclonal Antibody (10F2)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC452	Anti-AGR2 Antibody (10F2)	Mouse IgG1, Kappa	None	$460	In stock	Add
ASPC452-P	Anti-AGR2 Antibody (10F2), PE	Mouse IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC452-A	Anti-AGR2 Antibody (10F2), APC	Mouse IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC452-H	Anti-AGR2 Antibody (10F2), HRP	Mouse IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC452-B	Anti-AGR2 Antibody (10F2), Biotin	Mouse IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC452

Anti-AGR2 Antibody (10F2)

Mouse IgG1, Kappa

None

$460

In stock

Add

ASPC452-P

Anti-AGR2 Antibody (10F2), PE

Mouse IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC452-A

Anti-AGR2 Antibody (10F2), APC

Mouse IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC452-H

Anti-AGR2 Antibody (10F2), HRP

Mouse IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC452-B

Anti-AGR2 Antibody (10F2), Biotin

Mouse IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-AGR2 Monoclonal Antibody (10F2)
- Product Description:
  
  The Anti-AGR2 antibody is a mouse monoclonal antibody recommended for use in immunohistochemistry, immunoprecipitation, blocking and other applications. This antibody specifically targets AGR2 and demonstrates reactivity with human.
  
  Applications:
  
  Immunohistochemistry, Immunoprecipitation, Blocking
  
  Target:
  
  AGR2
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human AGR2.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  10F2
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-AGR2 Monoclonal Antibody (10F2) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

AGR2

Protein Name

Anterior gradient protein 2 homolog

Introduction

Anterior gradient protein 2 homolog (AGR-2), also known as secreted cement gland protein XAG-2 homolog, is a protein that in humans is encoded by the AGR2 gene. Anterior gradient homolog 2 was originally discovered in Xenopus laevis. In Xenopus AGR2 plays a role in cement gland differentiation, but in human cancer cell lines high levels of AGR2 correlate with downregulation of the p53 response, cell migration, and cell transformation. However, there have been other observations that AGR2 can repress growth and proliferation.

Alternative Names

AGR2; anterior gradient 2, protein disulphide isomerase family member; AG2; GOB-4; HAG-2; XAG-2; PDIA17; HEL-S-11

Gene ID

10551

UniProt

O95994

Related Disease

Respiratory infections, recurrent, and failure to thrive with or without diarrhea (RIFTD)

Subcellular Location

Secreted

Cell Line Specificity

Cancer enhanced

Function

Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity).

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