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Anti-AASDHPPT Monoclonal Antibody (H-11D9)
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Product Description:The Anti-AASDHPPT antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human AASDHPPT.Applications:Immunohistochemistry, Immunocytochemistry, Western Blot, ImmunoprecipitationSource:MouseTarget:AASDHPPTTarget Species:HumanSpecificity:This antibody reacts with human Aminoadipate-Semialdehyde Dehydrogenase-Phosphopantetheinyl Transferase (AASDHPPT).Clonality:MonoclonalClone ID:H-11D9Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEConcentration:1 mg/mLForm:LiquidFormulation:Contact us for custom product formulation.Preservative:0.02% sodium azideShipping:Shipped at 4°C.Storage:This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
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Anti-AASDHPPT Monoclonal Antibody (H-11D9) Applications
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Recommended Dilution:Western Blot: 1:500-1:5000
Immunohistochemistry: 1:50-1:200
Immunocytochemistry: 1:50-1:200Note:Optimal dilutions/concentrations should be determined by the end user.
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Protein Name
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
Introduction
The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.
Alternative Names
AASD-PPT; ACPS; CGI-80; LYS2; LYS5
Gene ID
UniProt
Subcellular Location
Cytoplasm, cytosol
Tissue Specificity
Detected in heart, skeletal muscle, placenta, testis, brain, pancreas, liver and kidney.
Cell Line Specificity
Low cancer specificity
Function
Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'-phosphopantetheine moiety from coenzyme A, regardless of whether the CoA is presented in the free thiol form or as an acetyl thioester, to a serine residue of a broad range of acceptors including the acyl carrier domain of FASN.
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