UGT2B7

Full Name: UDP Glucuronosyltransferase Family 2 Member B7

BACKGROUND: The protein encoded by this gene belongs to the UDP-glycosyltransferase (UGT) family. UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein is localized in the microsome membrane, and has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Alternative splicing results in multiple transcript variants.

Synonyms: UDPGT 2B7; UDPGT 2B9; UDPGT2B7; UDPGTH2; UDPGTh-2; UGT2B9