Full Name: Mitochondrially Encoded NADH:Ubiquinone Oxidoreductase Core Subunit 5
BACKGROUND: Enables NADH dehydrogenase (ubiquinone) activity. Involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Located in mitochondrial inner membrane. Part of respiratory chain complex I. Implicated in Leber hereditary optic neuropathy; Leigh disease; and MELAS syndrome.
Synonyms: MTND5; ND5
Research Areas: Metabolism
Pathways: Metabolism Pathway
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