Full Name: Kruppel Like Factor 10
BACKGROUND: This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants.
Synonyms: EGR-alpha; EGRA; TIEG; TIEG1
Research Areas: Epigenetics
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